Quadruple Marker Test In Chennai

Overview of the Quadruple Marker Test

Test Overview

The Quadruple Marker Test, also known as the Quad Screen, is a prenatal screening test performed between 15 to 20 weeks of pregnancy to assess the risk of certain birth defects and fetal complications. It measures the levels of four substances in a pregnant woman’s blood: Alpha-fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Estriol, and Inhibin-A. This test helps estimate the likelihood of chromosomal abnormalities such as Down syndrome (Trisomy 21) and Edwards syndrome (Trisomy 18), as well as neural tube defects like spina bifida. While the Quadruple Marker Test does not provide a definitive diagnosis, it helps identify pregnancies that may require further evaluation. If the results indicate an increased risk, additional diagnostic tests such as amniocentesis or chorionic villus sampling (CVS) may be recommended for confirmation.

Tests Included in Quadruple Marker Test in Chennai

Here are the key components measured in the Quadruple Marker Test:

1.Alpha-fetoprotein (AFP)

• A protein produced by the baby’s liver and yolk sac.
• Helps assess the risk of neural tube defects, such as spina bifida, and other abnormalities in fetal development.

2.Human Chorionic Gonadotropin (hCG)

• A hormone produced by the placenta during pregnancy.
• Abnormal levels can indicate chromosomal conditions like Down syndrome (Trisomy 21).

3.Unconjugated Estriol (uE3)

• A form of estrogen produced by the fetus and the placenta.
• Low levels might suggest conditions such as Edward’s syndrome (Trisomy 18) or other developmental problems.

4.Inhibin-A

• A hormone secreted by the placenta.
• Elevated levels are associated with an increased risk of Down syndrome.

What Medical Treatments/Procedures Can Require the Quadruple Marker Test?

The Quadruple Marker Test is a prenatal screening test that helps assess the risk of certain genetic and developmental conditions in a fetus. While it is commonly recommended as part of routine prenatal care, it may be specifically required in the following cases:

• High-Risk Pregnancies: Women over 35 years old, those with a history of genetic disorders, or those with previous pregnancy complications may need the test to evaluate potential fetal abnormalities.
• Assisted Reproductive Techniques (ART): Women who have conceived through in vitro fertilization (IVF) or other fertility treatments may be advised to undergo this test for additional screening.
• Abnormal First-Trimester Screening Results: If earlier screening tests (such as the First Trimester Combined Test) indicate potential risks, the Quadruple Marker Test may be recommended for further assessment.
• Maternal Health Conditions: Pregnant individuals with diabetes, obesity, or hypertension may require additional fetal screenings, including the Quadruple Marker Test, to monitor the baby’s health.
• Exposure to Teratogens: Women who have been exposed to radiation, infections, certain medications, or harmful chemicals may be advised to take the test to assess potential fetal complications.
• History of Neural Tube Defects (NTDs): If there is a family history of spina bifida or other NTDs, this test can help evaluate the risk in the current pregnancy.
  If the Quadruple Marker Test results indicate an increased risk, further diagnostic procedures, such as amniocentesis or chorionic villus sampling (CVS), may be recommended for confirmation.

Test Requirements

The Quadruple Marker Test is a simple blood test that requires minimal preparation. Here are the key requirements:

• Timing: The test is usually performed between 15 to 20 weeks of pregnancy, with the optimal window being 16 to 18 weeks for more accurate results.
• Fasting: No fasting is required; the test can be done at any time of the day.
• Blood Sample: A small blood sample is drawn from the mother’s arm for analysis.
• Medical History: The doctor may ask for details like maternal age, weight, gestational age, and medical history, as these factors influence the test results.
• Doctor’s Prescription: A prescription or recommendation from a healthcare provider is typically needed before taking the test.

Since the Quadruple Marker Test is a screening test and not a diagnostic test, abnormal results may require further testing, such as ultrasound, amniocentesis, or chorionic villus sampling (CVS), for confirmation.

Price of the Quadruple Marker Test in Chennai

Quadruple Marker Test  Price in Different Cities

The Quadruple Marker Test price in India can vary based on the laboratory, location, and additional services offered.

• Test Type: This second-trimester prenatal screening measures levels of specific substances in the mother's blood to assess the risk of genetic disorders and birth defects in the baby. It is a standard test offered by diagnostic centres and hospitals.
• Location: The geographical area where the test is conducted can greatly influence the cost. In metropolitan cities like Mumbai, Delhi, or Bangalore, the cost may be slightly higher due to advanced facilities and greater demand. In smaller towns, the test might be comparatively more affordable but could have limited availability.
• Lab Quality: The reputation and technology of the laboratory play a role in the cost. Premium diagnostic centres equipped with cutting-edge technology and expert professionals may charge higher rates, but they provide more reliable and accurate results.
• Additional Services: Services like home sample collection, quicker result delivery, or online consultations with doctors might add to the overall cost. These conveniences, while helpful, may come with an additional fee depending on the provider.
• Discounts and Promotions: Many diagnostic centres, such as Apollo 24|7, often provide discounts or bundled packages for prenatal tests, reducing the total quadruple test price. Be sure to check the latest deals on their official websites or apps to make the most of these savings.

Reports of the Quadruple Marker Test

Here’s a breakdown of the components, normal range, and what deviations from the normal range indicate:

Note: The interpretation of Quadruple Marker Test results must consider maternal factors such as age, weight, and medical conditions, as these can affect marker levels. Abnormal results should be assessed alongside clinical findings, and further diagnostic tests, like amniocentesis, may be required for confirmation.

How Often Should You Be Recommended Quadruple Marker Test?

The Quadruple Marker Test is a one-time prenatal screening test that is typically performed once between the 15th and 20th weeks of pregnancy, with the optimal time being around the 16th to 18th week.

It is not a repeated test unless specific concerns arise, such as:

• Abnormal First-Trimester Screening Results: If earlier tests indicate a potential risk of fetal abnormalities, doctors may recommend additional screenings.
• Unclear or Borderline Results: If initial Quadruple Marker Test results are inconclusive, a repeat test or further diagnostic procedures like amniocentesis may be advised.
• High-Risk Pregnancies: In cases of maternal health conditions, genetic predispositions, or multiple pregnancies, doctors may suggest further evaluation beyond this test.

Since the Quadruple Marker Test is a screening tool rather than a diagnostic test, it is generally performed only once unless further assessments are necessary based on the results.

Book the Quadruple Marker Test Online

Booking a Quadruple Marker Test through Apollo 24|7 is convenient and can be done from the comfort of your home. Follow these easy steps:

1.Visit Apollo 24|7 Website or App:

Start by visiting the official Apollo 24|7 website or download their easy-to-use mobile app from the App Store or Google Play. The platform is designed to be intuitive and user-friendly for hassle-free navigation.

2.Search for the Test:

On the homepage, locate the search bar, typically positioned at the top of the page. Type in “Quadruple Marker Test” or “Maternal Serum Screening” to find the specific test page related to the quadruple marker test, which screens for chromosomal abnormalities like Down syndrome, Trisomy 18, and neural tube defects.

3.Select a Convenient Time and Location:

Once you are on the Quadruple Marker Test page, choose a suitable time slot for the test and select your preferred location from the available collection centres or diagnostic facilities. You will also find information on the test cost on this page.

4.Complete Your Booking:

After choosing your time and location, fill in your details to complete the booking process. Ensure all the information provided is correct to avoid any issues during the test.

5.Wait for Confirmation:

After completing the booking, you will receive a confirmation message or email from Apollo 24|7 verifying your booking details. This confirms that your test request has been successfully processed.