Coombs Test (Indirect) in Hyderabad

Test Overview

Overview of the Coombs Test (Indirect) in Hyderabad

The Coombs test (indirect), also known as the indirect antiglobulin test (IAT), is a blood test that detects the presence of antibodies in the serum that could potentially react with red blood cells. These antibodies are produced by the immune system in response to foreign red blood cells, such as those from a different blood type or during pregnancy. The test helps identify whether these antibodies are present, which is crucial in preventing adverse reactions during blood transfusions and managing pregnancies to protect the foetus from maternal antibodies. The Coombs test (indirect) in Hyderabad is a valuable tool for ensuring safe blood transfusions and monitoring maternal-foetal compatibility.

Apollo offers a Coombs Test (Indirect) test across many cities such as:

You can also download the Apollo 24|7 App for a better experience.

Tests Included in Coombs Test (Indirect) 

The Coombs test (indirect) is a single test rather than a package of multiple tests, but it can be part of a broader set of tests used in immunohematology.

• Coombs Test (Indirect): The test involves isolating the serum from a blood sample and incubating it with non-patient RBCs of known antigenicity. Anti-human globulin (Coombs reagent) is then added to the mixture. If agglutination (clumping of RBCs) occurs, the test is positive, indicating the presence of antibodies against the RBCs.

The optional test includes:

• Titre: Depending on the results, additional tests may be conducted to identify the specific type of antibody present and its clinical significance. These can include antibody identification, RBC phenotyping, and titration studies to determine the concentration of the antibodies.

What Conditions Can Be Diagnosed with the Coombs Test (Indirect)?

The Coombs test (indirect) is used to diagnose and manage various conditions related to antibodies against red blood cells. The most common conditions that can be diagnosed with this test include:

• Haemolytic Disease of the Newborn (HDN): This condition occurs when maternal antibodies cross the placenta and attack the foetus's red blood cells. The test helps identify if the mother has harmful antibodies.
• Incompatible Blood Match: Before a blood transfusion, the test ensures that the recipient's blood does not contain antibodies that would react against the donated blood, preventing a transfusion reaction.
• Autoimmune Haemolytic Anaemia: While primarily diagnosed with the direct Coombs test, the indirect test can sometimes detect antibodies contributing to autoimmune haemolytic anaemia.
• Prenatal Antibody Screening: The test screens pregnant women for antibodies that could pose a risk to the foetus, allowing for early intervention and management.

Coombs Test (Indirect) Requirements in Hyderabad

To undergo the indirect Coombs test in Hyderabad, there are a few requirements to keep in mind:

• There are no specific dietary requirements or preparations needed for the Coombs test (indirect).
• A phlebotomist will collect a blood sample from a vein in the arm or hand using a needle. The process involves a small skin prick and may result in minor bleeding or bruising at the needle insertion site.
• The blood sample is then sent to a laboratory for analysis.

Price of the Coombs Test (Indirect) in Hyderabad

The indirect Coombs test price in Hyderabad can vary depending on the doctor and the specific laboratory. Factors such as the location of the facility, the equipment used, and the expertise of the staff can all contribute to the final cost. On average, the Coombs test price in Hyderabad ranges from Rs____ to Rs_____.

Reports of the Coombs Test (Indirect)

The Coombs test (indirect) report typically presents the results as either positive or negative:

Note: The interpretation of these results can vary depending on the laboratory, age, sex, and underlying conditions.

How Often Should You be Recommended the Coombs Test (Indirect)?

The frequency of the indirect Coombs test depends on specific circumstances and clinical guidelines. Here are some general recommendations for when the test is performed:

• Pregnant Women: The test is typically done during the first prenatal visit (usually in the first trimester) to check for Rh incompatibility and other antibodies. A follow-up test is often performed in the third trimester (around 28 weeks) to identify any new antibodies that may develop as the pregnancy progresses.
• Blood Donors: The test is conducted at the time of blood donation as part of routine screening to ensure the safety of the blood supply.
• Patients Preparing for Blood Transfusion: The test is performed whenever a patient is scheduled for a blood transfusion to assess compatibility with donor blood. This is generally done for each transfusion.
• Individuals with Autoimmune Disorders or Hemolytic Anemia: The test may be recommended periodically based on clinical findings and the patient's condition, rather than on a regular schedule. The frequency can vary based on the stability of the condition and any changes in symptoms.
• Neonates: Newborns suspected of having hemolytic disease are typically tested shortly after birth, especially if the mother is known to have antibodies.

Book a Coombs Test (Indirect) Online

Booking a Coombs test in Hyderabad through Apollo 24|7 is a simple and convenient process that can be completed online. Here's a step-by-step guide:

• Visit the Apollo 24|7 website or download the app on your smartphone.
• Use the search function to find "Coombs Test (Indirect) in Hyderabad" or "Indirect Coombs Test in Hyderabad".
• Select a suitable time slot and location for your blood sample collection.
• Complete the booking process by providing the necessary details and making the payment.
• Wait for a confirmation message from Apollo 24|7 regarding your indirect Coombs test in Hyderabad.