Coombs Test (Indirect) in Delhi

Test Overview

Overview of the Coombs Test (Indirect) in Delhi

The Coombs test (indirect), also known as the indirect antiglobulin test (IAT), is a blood test that detects the presence of antibodies in the serum that could potentially react with red blood cells. These antibodies are produced by the immune system in response to foreign red blood cells, such as those from a different blood type or during pregnancy. The test helps identify whether these antibodies are present, which is crucial in preventing adverse reactions during blood transfusions and managing pregnancies to protect the foetus from maternal antibodies. The Coombs test (indirect) in Delhi is a valuable tool for ensuring safe blood transfusions and monitoring maternal-foetal compatibility.

Apollo offers a Coombs Test (Indirect) test across many cities such as:

You can also download the Apollo 24|7 App for a better experience.

Coombs Test (Indirect) Requirements in Delhi

To undergo the indirect Coombs test in Delhi, there are a few requirements to keep in mind:

• There are no specific dietary requirements or preparations needed for the Coombs test (indirect).
• A phlebotomist will collect a blood sample from a vein in the arm or hand using a needle. The process involves a small skin prick and may result in minor bleeding or bruising at the needle insertion site.
• The blood sample is then sent to a laboratory for analysis.

Tests Included in Coombs Test (Indirect) 

The Coombs test (indirect) is a single test rather than a package of multiple tests, but it can be part of a broader set of tests used in immunohematology.

• Coombs Test (Indirect): The test involves isolating the serum from a blood sample and incubating it with non-patient RBCs of known antigenicity. Anti-human globulin (Coombs reagent) is then added to the mixture. If agglutination (clumping of RBCs) occurs, the test is positive, indicating the presence of antibodies against the RBCs.

The optional test includes:

• Titre: Depending on the results, additional tests may be conducted to identify the specific type of antibody present and its clinical significance. These can include antibody identification, RBC phenotyping, and titration studies to determine the concentration of the antibodies.

Who Should Get the Coombs Test (Indirect) Done?

The indirect Coombs test is typically performed on specific populations and under certain circumstances. Here are the key groups and situations where this test is recommended:

• Pregnant Women: Pregnant women, especially those with Rh-negative blood type, are screened during the first prenatal visit and again in the third trimester to check for antibodies that could affect the fetus (e.g., in cases of Rh incompatibility).
• Blood Donors: Blood donors may undergo the indirect Coombs test to identify any antibodies that could react with donor red blood cells during transfusion.
• Patients Preparing for Blood Transfusion: Before a blood transfusion, the test is performed to ensure the recipient does not have antibodies that could react with the donated blood, preventing hemolytic transfusion reactions.
• Individuals with Autoimmune Disorders: Patients with conditions like systemic lupus erythematosus (SLE) or other autoimmune disorders may be tested for antibodies against their own red blood cells.
• Patients with Hemolytic Anaemia: In cases of suspected hemolytic anemia, the indirect Coombs test may be part of the workup to identify underlying antibodies contributing to the condition.
• Neonates: Newborns with signs of hemolytic disease may be tested to determine if maternal antibodies are involved.

Price of the Coombs Test (Indirect) in Delhi

The indirect Coombs test price in Delhi can vary depending on the doctor and the specific laboratory. Factors such as the location of the facility, the equipment used, and the expertise of the staff can all contribute to the final cost. On average, the Coombs test price in Delhi ranges from Rs____ to Rs_____.

Reports of the Coombs Test (Indirect)

The Coombs test (indirect) report typically presents the results as either positive or negative:

Note: The interpretation of these results can vary depending on the laboratory, age, sex, and underlying conditions.

Lifestyle Changes to Reach a Normal Range on the Coombs Test (Indirect)

While lifestyle changes alone cannot directly impact the results of the Coombs test (indirect), as it primarily detects pre-existing antibodies, there are a few general considerations:

• Maintaining overall good health can help minimise the production of unnecessary antibodies.
• For individuals who have had multiple blood transfusions and developed various antibodies, minimising transfusions can reduce the complexity of finding compatible blood.
• For pregnant women, regular prenatal care and monitoring can help manage any risks associated with maternal antibodies.

Book a Coombs Test (Indirect) Online

Booking a Coombs test in Delhi through Apollo 24|7 is a simple and convenient process that can be completed online. Here's a step-by-step guide:

• Visit the Apollo 24|7 website or download the app on your smartphone.
• Use the search function to find "Coombs Test (Indirect) in Delhi" or "Indirect Coombs Test in Delhi".
• Select a suitable time slot and location for your blood sample collection.
• Complete the booking process by providing the necessary details and making the payment.
• Wait for a confirmation message from Apollo 24|7 regarding your indirect Coombs test in Delhi.