LE Cell

Systemic Lupus Erythematosus (SLE) is an autoimmune disorder that is known to cause inflammation throughout the body. The condition occurs when the immune system attacks healthy tissues and organs of the body. SLE can affect any part of the body, including the skin, joints, kidneys, brain, and other organs. It is a chronic disease that can last for years or even a lifetime. LE Cell test is a laboratory test that helps in detecting the presence of antibodies in the blood that is commonly found in individuals with SLE.

Symptoms

The symptoms of SLE can vary greatly from person to person and may come and go over time. Some of the common symptoms associated with systemic lupus erythematosus:

Fatigue: Persistent and extreme fatigue is a common symptom of SLE. It can significantly impact daily activities and quality of life.
Joint pain and swelling: SLE often causes joint pain, stiffness, and swelling, typically affecting multiple joints. The pain can be migratory and may be more pronounced in the morning or after periods of inactivity.
Skin rashes: Skin rashes are a characteristic feature of SLE. The most common rash is a butterfly-shaped rash across the cheeks and bridge of the nose (malar rash). Other types of skin rashes may appear as well, such as a discoid rash (red, scaly patches), photosensitivity (rashes triggered by sun exposure), or a rash on other parts of the body.
Fever: Many individuals with SLE experience low-grade fevers (below 38.3°C or 101°F) that may occur intermittently.
Raynaud's phenomenon: Raynaud's phenomenon is characterized by the temporary constriction of blood vessels in response to cold temperatures or stress, leading to colour changes (pallor, cyanosis, or redness) in the fingers and toes.
Kidney problems: SLE can cause inflammation in the kidneys (lupus nephritis), leading to symptoms such as blood or protein in the urine, increased urination, high blood pressure, and swelling in the legs or ankles.
Chest pain: SLE can affect the heart and lungs, leading to symptoms like chest pain, shortness of breath, or inflammation of the lining around the heart (pericarditis).
Photosensitivity: People with SLE may be sensitive to sunlight or artificial light, which can trigger or worsen symptoms such as skin rashes, fatigue, and joint pain.
Hair loss: Hair loss, often characterized by patches of hair thinning or scalp involvement, can occur in individuals with SLE.
Neurological symptoms: SLE can affect the nervous system, leading to symptoms like headaches, cognitive difficulties (memory problems, confusion), seizures, and peripheral neuropathy (numbness, tingling, or pain in the extremities).

It's important to note that these symptoms can also be caused by other conditions, and SLE can present differently in different individuals. If you are experiencing persistent or concerning symptoms, it is important to consult a healthcare professional for a proper evaluation and diagnosis.

Sample Procurement Method

LE Cell test requires a simple blood sample from the individual being tested. The healthcare professional will insert a needle into the vein, typically on the arm. They will then collect the blood into a vial or syringe. The procedure usually takes only a few minutes, and there is no need for any special preparations.

Test Procedure

The collected blood sample is sent to a specialized laboratory where it undergoes testing for antinuclear antibodies (ANAs). ANAs are generally present in individuals with autoimmune disorders like SLE. The LE Cell test is a type of ANA test that specifically detects the presence of antibodies called LE cells in the blood. If the test results come out positive, it suggests that the individual has SLE.

Treatment

There is no cure for SLE, but early diagnosis and treatment can help control symptoms and prevent complications. Treatment options for SLE may include medications like anti-inflammatory drugs, corticosteroids, immunosuppressants, and antimalarials. Management of SLE also involves lifestyle changes like regular exercise, a healthy diet, getting sufficient rest, avoiding triggers like sunlight exposure, and managing stress levels.

Booking a Slot for LE Cell Test

Booking a slot for the LE Cell test has been made easy by Apollo 24|7. One can book an appointment on the website or mobile app in a matter of minutes. Once the booking is confirmed, the individual can visit any Apollo 24|7 diagnostic centre to get their blood sample collected. The test reports are generally available within 48 hours of sample collection.

Benefits of Early Diagnosis

Early diagnosis of SLE can help slow down disease progression, prevent complications, and improve the quality of life of the individual. Early diagnosis can also help in the timely initiation of treatment, which may lead to better outcomes. Additionally, early diagnosis can help reduce healthcare costs associated with complications that arise from undiagnosed autoimmune disorders like SLE.