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Gastrin - Serum in Nandhini Layout, Bangalore

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  • GASTRIN - SERUM

    1 test included

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About

blood sample
SAMPLE TYPE

BLOOD

Gender
GENDER

Both

users
AGE GROUP

7 years & above

Gastrin is a hormone produced by the stomach to aid in the production of gastric acid. It is required by the body to fully absorb nutrients from meals, notably proteins and amino acids. A gastrin serum test checks for high levels of gastrin synthesis in the stomach.

Every day, the stomach produces 2 to 3 litres of acidic fluid. Anything exceeding these thresholds can indicate a number of problems, including:

  • Chronic kidney disease
  • Infection of the stomach or Helicobacter pylori
  • Chronic gastritis
  • Use of antacids or medication to treat heartburn
  • Overactivity of the stomach's gastrin-producing cells (G-cell hyperplasia)
  • History of stomach surgery
  • Reduced stomach acid production capacity
  • Zollinger-Ellison syndrome characterised by the development of a gastrin-producing tumour in the stomach or pancreas

You may also experience digestive issues if your gastrin levels are either too high or too low. Furthermore, if you have recurring symptoms such as stomach aches, diarrhoea, or peptic ulcers, you may be required to take the gastrin test. If you previously had a gastrin-producing tumour removed, your doctor may also conduct a routine gastrin serum test to ensure that the tumour has not come back.

You must fast for approximately 12 hours before the Gastrin serum test. You should also abstain from alcohol for 24 hours before the Gastrin serum test. Inform your doctor if you take any medication, supplements, prescription drugs, over-the-counter medicines and/or illegal narcotics before the Gastrin test.

Certain other aspects can also affect the results of the gastrin serum test. Thus, you should inform your healthcare provider of the following:

  • Consume a high-protein diet
  • Diabetes and the use of insulin
  • Have had or intend to have a peptic ulcer surgery
  • Caffeine consumption
  • Take antidepressant medication
  • Take calcium antacids, supplements, H2-blocking drugs, proton pump inhibitors, or other medications that may affect the capacity to create stomach acid

A variety of circumstances might influence the Gastrin serum test results. They may also differ depending on the laboratory and the benchmark ranges. The average range for gastrin levels is:

  • 0-180 pg/mL for adults
  • 0-125 pg/mL for children

A very high gastrin level usually results in a disorder known as Zollinger-Ellison syndrome. Extra Gastrin might produce an excess of acid within the digestive tract. This causes diarrhoea and ulcers in the stomach and the small intestine. However, Zollinger Ellison syndrome is fully curable.

Nevertheless, the first step is to get a Gastrin serum test, as ordered by your medical provider. Apollo 24/7 offers a Gastrin serum test at an affordable price. You simply need to book one through the website.

Once the results are in, your medical provider can offer you appropriate treatment plans, including:

  • Getting rid of as much of the liver tumour as possible through debulking
  • Using embolization or radiofrequency ablation to destroy the tumour
  • Liver transplant
  • Chemotherapy to decrease tumour development
  • Alleviating cancer symptoms by injecting medicines into the tumour
     

Medically reviewed by Dr. Naveen Polavarapu, Gastroenterologist, Apollo Hospitals Jubilee Hills, Hyderabad

faqFrequently Asked Questions (FAQs)

What are some preparations for the Gastrin test that one needs to undertake to ensure accurate results?

You must avoid eating for 12 hours and abstain from alcohol for 24 hours before the Gastrin serum test. Your healthcare provider may also advise you to avoid using certain gastrointestinal medications for a few days before the test. This is because certain medicines might raise gastrin levels, hence affecting the report.

What are some medicines that can spike Gastrin levels?

Antacids, H2-blocking drugs like cimetidine and famotidine, and proton pump inhibitors like omeprazole and pantoprazole can all raise gastrin levels.

When should one take a Gastrin Serum test?

If a person has diarrhoea, experiences recurrent peptic ulcers, or gastrointestinal discomfort that does not respond to medication that the medical provider suspects is caused by increased gastrin production, they may suggest a gastrin serum test. Alternatively, the medical provider might order a Gastrin serum test to screen those who have had a Gastrin tumour removed.

What are the normal levels of Gastrin in the system?

Average values for a gastrin serum test vary between labs. They are, on average, 0-180 pg/mL for adults and 0-125 pg/mL for children.

What is the Zollinger-Ellison syndrome?

Zollinger-Ellison syndrome is distinguished by elevated gastrin levels and increased production of stomach acid. Zollinger-Ellison syndrome occurs when gastrinomas, or gastrin-producing tumours, grow in the stomach, pancreas, or the duodenum and, on rare occasions, in other regions of the body. Most of them are cancerous and can spread to other regions of the body.

What are some treatments used to address Zollinger-Ellison syndrome?

Treatments for Zollinger-Ellison syndrome typically include destroying the cancerous tumours using chemotherapy. Alternatively, doctors suggest surgery to remove part of the liver or undergo a transplant.

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results