ENA, Qualitative Profile in Medavakkam, Chennai

ENA, Qualitative Profile

Test Overview

What is an ENA, Qualitative Profile Test?

The extractable nuclear antigen test, also known as ENA test, is a crucial diagnostic tool that analyses specific antibodies in your blood. These antibodies are associated with various autoimmune disorders and are often present when your immune system erroneously targets your body's tissues, leading to inflammation and harm. The ENA profile test looks for antibodies against several proteins found in the cell nucleus, helping doctors distinguish between different autoimmune conditions and monitor disease progression.

The top ENA, Qualitative Profile tests are available in Hyderabad, Bangalore, Gurgaon, Noida, Chennai.

Understanding the importance of the anti ENA test can significantly contribute to enhancing your overall health. This ENA screen test is particularly recommended for patients who have tested positive for antinuclear antibodies (ANA) and exhibit symptoms indicative of autoimmune diseases like systemic lupus erythematosus (SLE), Sjögren syndrome, scleroderma, and mixed connective tissue disease (MCTD). By identifying the presence or absence of these antibodies, doctors can set a path for the diagnostic process and ongoing management of autoimmune diseases.

What is the ENA, Qualitative Profile Test Price?

Assessing the price of ENA screen testing involves considering several elements. Here are key factors to consider when examining the ENA profile test price:

• Test Demand: The demand for the ENA blood test can influence its price. You might find slightly elevated costs in metro cities like Ahmedabad, Bengaluru, Chennai, and Delhi where demand for these tests may be higher.
• Comprehensive Inclusions: The ENA test price usually encompasses various charges including laboratory fees, sample collection charges, and any applicable professional fees. It’s important to understand what these charges included in your total cost to ensure transparency and avoid any unexpected expenses.
• Laboratory Quality: The quality of the lab conducting the ENA qualitative test plays a significant role in its price. Labs with state-of-the-art equipment and stringent quality control procedures might have a higher ENA profile test price. It's always wise to opt for a certified laboratory known for its accuracy and reliability when it comes to conducting an ENA test.
• Discounts and Promotions: Many healthcare centres often provide discounts or packages for diagnostic tests like the ENA profile test, which can considerably bring down your overall expenditure. These offerings may also include information about the anti ENA test range, providing you with a comprehensive understanding of your test results.

Before proceeding with an ENA screen testing, one should check the ENA test price across their city. This will help in making an informed choice about where to have the test conducted.

What is the Purpose of an ENA, Qualitative Profile Test?

The extractable nuclear antigen test plays a significant role in diagnosing and managing autoimmune disorders. Here's why an ENA screen test is essential:

• Diagnosis of Autoimmune Disorders: By detecting autoantibodies that react against nuclear proteins, the ENA test helps identify the presence of autoimmune diseases. A positive result, alongside a positive antinuclear antibody (ANA) test, can point towards specific autoimmune conditions.
• Identification of Specific Antibodies: The anti ENA test analyses antibodies against a group of proteins that may include Ro, La, Sm, RNP, Scl-70, and Jo1. Each antibody is linked to different autoimmune conditions helping to differentiate between them.
• Monitoring Disease Activity: The ENA blood test can monitor disease progression and response to treatment for individuals already diagnosed with autoimmune conditions. This information aids in adjusting therapeutic strategies effectively.
• Understanding Autoimmune Responses: The ENA profile test offers insights into the nature of an individual's autoimmune response by identifying specific autoantibodies. This knowledge can help customise treatment strategies and improve disease management.
• Clinical Correlation: The results of extractable nuclear antigen tests are interpreted alongside clinical findings and symptoms. This comprehensive approach ensures accurate diagnosis and patient care.

Who Should Get an ENA, Qualitative Profile Test Done?

Understanding who would require an ENA profile test can lead to timely diagnosis and efficient treatment of potential autoimmune disorders. Here's who should consider getting this ENA test done:

• Individuals with Unexplained Symptoms: If you're experiencing symptoms such as fatigue, joint pain, or muscle weakness that might hint towards an autoimmune disorder, it's advisable to get an ENA qualitative test done.
• Positive ANA Test Results: The ENA profile test is typically ordered after a positive antinuclear antibody (ANA) test. The presence of autoantibodies in the blood can be further investigated via an ENA test.
• Diagnosis of Specific Autoimmune Disorders: The ENA screen test helps diagnose conditions like lupus, Sjögren's syndrome, scleroderma, and mixed connective tissue disease.
• Monitoring Existing Conditions: If you have been diagnosed with an autoimmune disorder, undergoing an ENA profile test can monitor disease activity or progression, particularly if new symptoms arise.
• Clinical Evaluation: The ENA blood test is a part of a wider diagnostic approach. The results should be interpreted alongside clinical findings and other laboratory tests to confirm a diagnosis.

Components of an ENA, Qualitative Profile

When you undertake an extractable nuclear antigen test, it checks for various components in your blood. Understanding these components can give you a clearer picture of your health. Here are the key components:

• dsDNA: Double-stranded DNA (dsDNA) is the molecule that carries genetic information in cells, forming a double helix structure. It is crucial for genetic replication and cellular function.
• Nucleosomes: Nucleosomes are the fundamental units of chromatin, consisting of DNA wrapped around a core of histone proteins. They help in organising and compacting the DNA within the nucleus.
• Histones: Histones are proteins that package and order DNA into structural units called nucleosomes. They play a key role in gene regulation and chromatin dynamics.
• Ku: Ku is a protein complex involved in the repair of DNA double-strand breaks through non-homologous end joining. It binds to the ends of broken DNA and recruits other repair factors.
• SmD1: SmD1 is a protein component of the small nuclear ribonucleoproteins (snRNPs), which are essential for splicing pre-mRNA. It is a part of the machinery that removes introns from RNA transcripts.
• PCNA: Proliferating cell nuclear antigen (PCNA) is a protein that acts as a processivity factor for DNA polymerase during DNA replication. It helps in maintaining the stability of the DNA replication complex.
• Rib-P0: Ribosomal protein P0 is a component of the ribosome, involved in protein synthesis. It is essential for the formation and function of the ribosomal subunits.
• SS-A/Ro60: SS-A/Ro60 is a ribonucleoprotein antigen found in several autoimmune disorders. It is involved in RNA processing and has been linked to systemic lupus erythematosus and Sjögren's syndrome.
• SS-A/Ro52: SS-A/Ro52 is another autoantigen associated with autoimmune conditions, including lupus and Sjögren's syndrome. It is a component of the SS-A/Ro ribonucleoprotein complex.
• SS-B/La: SS-B/La is a ribonucleoprotein that interacts with nascent RNA molecules. It plays a role in RNA stability and processing and is also associated with autoimmune diseases.
• CENP-B: CENP-B is a centromere protein that binds to centromeric DNA and is crucial for the proper alignment and segregation of chromosomes during cell division. It is a key player in maintaining chromosome stability.
• Scl-70: Scl-70, or anti-Scl-70, is an antibody directed against topoisomerase I, an enzyme involved in DNA replication and repair. It is commonly associated with scleroderma.
• U1-snRNP: U1 small nuclear ribonucleoprotein (U1-snRNP) is involved in the splicing of pre-mRNA by recognising and binding to the 5' splice site of introns. It is a key component of the spliceosome.
• AMA-M2: Anti-mitochondrial antibody M2 (AMA-M2) targets mitochondrial proteins and is often associated with primary biliary cholangitis. It is used in diagnosing and monitoring liver diseases.
• J0-1: J0-1 is an autoantibody associated with various autoimmune diseases, particularly myositis. It targets histidyl-tRNA synthetase, an enzyme involved in protein synthesis.
• PM-Scl: PM-Scl is a complex of proteins that are part of the spliceosome and also involved in ribosome biogenesis. It is associated with polymyositis and scleroderma.
• Mi-2: Mi-2 is a component of the nucleosome remodeling and deacetylase (NuRD) complex, which is involved in transcription regulation and chromatin remodeling. It is also associated with certain autoimmune conditions, such as dermatomyositis.
• Control Band: A control band is a reference marker used in laboratory assays and diagnostic tests to ensure the accuracy and validity of the results. It helps verify that the test has been performed correctly and that the reagents are functioning properly.

Understanding an ENA, Qualitative Profile Test Report

Below are the what the values indicate by this diagnostic test:

Preparation and Procedure for an ENA, Qualitative Profile Test

Before you take an ENA screen test, it's crucial to know about the process and necessary preparations to ensure the most accurate results.

How is the ENA, Qualitative Profile Test Done?

Understanding how your ENA test will be performed can help you feel more comfortable and prepared during your visit to the hospital. Here's a step-by-step outline of what to expect during your ENA profile test:

• A healthcare professional will draw a blood sample. This is typically taken from a vein in your arm using a needle.
• This blood sample is then sent to a specialised laboratory for detailed analysis. The ENA blood test panel may include various tests to check for different autoantibodies.
• If the test result is positive, it signifies the presence of specific autoantibodies that help confirm a diagnosis of an autoimmune disorder. These results should be interpreted and explained by your doctor for correct understanding and subsequent action.
• In case the initial results from this anti ENA test come out negative, but symptoms persist, the doctor may suggest repeating the ENA profile test.
• Due to the specialised nature of this extractable nuclear antigen test, receiving your results might take up to 3 days.

Is Fasting Required for an ENA, Qualitative Profile Test?

Knowing whether fasting is necessary before undergoing an ENA screen testing is integral to securing accurate results. Let's explore this further:

• There's no need for you to fast before undergoing an ENA qualitative test. Your normal eating schedule won't affect the results of this test.
• It's always wise to discuss any concerns or queries with your doctor ahead of time. They will guide you on the preparation and inform you about anything that could impact the test's effectiveness.

What Time of the Day Should I Undergo an ENA, Qualitative Profile Test?

Determining the appropriate time for an ENA profile test can contribute to more accurate results. Let's look at the best time to schedule your ENA test and the benefits of adhering to that timing:

• There is no specific time of day required for your ENA blood test. You can schedule it at any time that suits your convenience.
• Depending on whether your blood sample will be used for further tests, you might need to fast for a period before the test to ensure reliable results.
• Your doctor will provide clear instructions on any necessary preparations prior to the ENA qualitative test.

Booking Your ENA, Qualitative Profile Test Online & Checking Reports

This segment will guide you through the straightforward process of scheduling an ENA test online at Apollo 24|7 and downloading the test report once it's ready.

What are the Steps to Schedule an ENA, Qualitative Profile Test on Apollo 24|7?

Organising an ENA profile test on Apollo 24|7 is as simple as can be. With their customer-friendly interface, you can book your test from the comfort of your home. Follow these easy steps:

• Visit Apollo 24|7 Website or App: Start by heading to the official Apollo 24|7 website or download their app on your mobile device. The layout is easy to navigate and user-friendly.
• Search for the Test: Once you're on the homepage, find the search box, usually situated at the top. Type in "extractable nuclear antigen test" or "ENA test". This will take you to the page dedicated to this essential blood test.
• Select a Convenient Time and Location: Now that you're on the ENA blood test page, choose a time slot and location that suits your schedule for your blood sample collection. Here, you also get to see the competitive ENA profile test price.
• Complete Your Booking: After selecting your preferred time and location, fill in all required details to complete your booking.
• Wait for Confirmation: After successfully placing an order for your ENA qualitative test, wait for a confirmation message from Apollo 24|7. This final step ensures that your booking has been properly filed.

How Do I Access My ENA, Qualitative Profile Test Results Online On Apollo 24|7?

Accessing your ENA screen testing results is just as straightforward as booking the test. Apollo 24|7's intuitive online platform makes it easy and convenient. You can access and review your extractable nuclear antigen test results without leaving your home. Here's how you can view your ENA profile test results:

• Await Notification: After the completion of your ENA test, Apollo 24|7 will send a notification once your results are ready for viewing.
• Log in to Your Account: Use your account details to log in to Apollo 24|7's website or mobile application.
• Find the Reports Section: Once logged in, locate and click on the 'Reports' section. This is where all your test results, including the ENA screen test, are stored.
• Choose Your Test: Browse through your saved reports and select the ENA profile test report.
• Download Report: Each report comes with a download option. Use this feature to save a copy of your ENA blood test report for future use or for consultations with your doctor.