Anti Ds-Dna By- IFA Qualitative in Undri, Pune

The Anti Ds-DNA antibodies, or Anti-Double Stranded DNA antibodies, are essentially anti-nuclear antibodies that are produced when your immune system fails to function correctly.

Under normal circumstances, antibodies are your first line of defense to ward off infections. But in this case, the Anti Ds-DNA antibodies cannot differentiate between 'self' and 'foreign' components in the body. As a result, they end up attacking your healthy cells, and significantly damaging the tissues and organs.

Moreover, this damage to your cells can be quite detrimental since these antibodies directly target the genetic material present inside the nucleus of the cell.

Therefore, you must opt for the Anti Ds-DNA Antibody Test to keep your rogue antibody levels in check. If not, there is a chance you might develop an autoimmune disorder because a high level of Anti Ds-DNA antibodies is primarily associated with Systemic Lupus Erythematosus (SLE). This is a deadly autoimmune disorder that will affect:

• Kidneys 
• Blood vessels
• Lungs 
• Heart
• Brain 
• Joints

Systemic Lupus Erythematosus usually appears in women between the ages of 15 to 40. It is also common among people with a darker complexion.

The cause of this dangerous disease is still unknown. However, it’s a fact that this disease gets activated when you come in contact with a trigger present in the environment. So, you must get the Anti Ds-DNA Antibody Test if you start noticing the following symptoms:
A butterfly-shaped rash on your nose and cheeks 

• Headache 
• Joint pain and swelling
• Extreme fatigue 
• Sensitivity to light 
• Fever
• Hair loss
• Chest pain

The Anti Ds-DNA Antibody Test uses various color modifications and antibodies to detect foreign substances in the blood sample. Your sample will be added to an apparatus consisting of antigens.

If your sample contains antibodies that match the antigens present in the apparatus, they will bind together. Once this is done, an enzyme is added to this mix of coherent antigens. If there is a color change, it means that you do have the Anti Ds-DNA antibodies in your bloodstream.

You need to keep certain things in mind while getting tested for Systemic Lupus Erythematosus. This test does not proceed like regular diagnostic checks, since its results will vary significantly with the patient's symptoms or their medical history. The result will also be affected due to the irregular occurrence of autoimmune diseases.

So, you need to consult your healthcare provider and seek guidance from them, since it might take quite some time to make sense of the DNA results.

Apollo 24|7’s Anti Ds-DNA Antibody Test results will be available within 8 days. Since interpreting the Anti Ds-DNA Antibody Test results can be difficult, here are some pointers to help you out:

• Upon the onset of the Systemic Lupus Erythematosus, there are two components of your immune system that go rogue and attack your cells: C3 and C4. 
• If the results show a low level of both C3 and C4, you have Lupus. 
• If the levels of both components are moderate, Lupus in your system is controlled. However, it could worsen as time passes. 
• If the C3 levels are low, you are safe for now. However, there is a chance you might develop Lupus Nephritis soon.