Abnormal Hb Studies (Hb Electrophoresis) in Cuc, Hyderabad
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- ABNORMAL HB STUDIES (HB ELECTROPHORESIS)
19 tests included
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Abnormal Hb Studies (Hb Electrophoresis)
Test Overview
Sample Type | Blood |
Reports Delivery | 5 days |
Price/Cost | ₹1400 |
Number of Tests Included | 19 |
What is an Abnormal Hb Studies (Hb Electrophoresis) Test?
Haemoglobin, a vital protein found in red blood cells, is responsible for carrying oxygen throughout the body. An abnormal Hb study analyses the different types of haemoglobin within the bloodstream. Haemoglobin variants can be inherited, and detecting them early can aid in managing and treating related health issues. The test separates different types of haemoglobin based on their electrical charge, allowing for a detailed analysis of an individual's haemoglobin composition.
The top Abnormal Hb Studies (Hb Electrophoresis) Test are available in Hyderabad, Bangalore, Gurgaon, Noida, Chennai.
Doctors often recommend the hemoglobin electrophoresis test for detecting abnormal variants of haemoglobin, which can indicate conditions such as anaemia, thalassaemia, or sickle cell anaemia. For individuals planning to start a family, this test is crucial in assessing whether they are carriers for such conditions.
Early detection through hemoglobin electrophoresis test allows for better management of potential health risks, ensuring appropriate medical care and genetic counselling. Additionally, this test is valuable in monitoring patients with known haemoglobin disorders, guiding treatment decisions, and assessing disease progression.
What is the Abnormal Hb Studies (Hb Electrophoresis) Test Price?
The hemoglobin electrophoresis test is generally affordable, but understanding the key factors that influence the Hb electrophoresis test price can assist in managing healthcare expenses effectively. Below are the primary factors affecting the Hb electrophoresis test cost:
- Demand for the Test: Prices may vary based on the demand for the HPLC blood test, particularly in major cities where higher demand can lead to slightly elevated costs.
- Laboratory Standards: The quality of the laboratory conducting the Hb electrophoresis test procedure influences the overall cost. Laboratories adhering to international standards and employing advanced technology with strict quality controls typically charge higher prices. Choosing accredited labs known for their reliability is crucial.
- Comprehensive Inclusions: The HPLC blood test price generally includes several components, such as laboratory fees, sample collection charges, and any other related professional fees. Additionally, information about the Hb electrophoresis test normal range may also be provided, giving you a comprehensive understanding of your test results. Knowing what these charges include ensures transparency and helps avoid unexpected expenditures.
- Discounts and Offers: Healthcare facilities frequently offer discounted rates or package deals for diagnostic tests such as the HPLC blood test, which substantially lowers the overall test prices.
Apollo 24|7 maintains competitive Hb electrophoresis test prices while ensuring high service standards. Before scheduling an HPLC blood test, it's advisable to compare prices across different locations.
What is the Purpose of an Abnormal Hb Studies (Hb Electrophoresis)Test?
The abnormal Hb studies (Hb electrophoresis) test plays a significant role in identifying and analysing different types of haemoglobin variants. The Hb electrophoresis test purpose is multifaceted, making it a vital tool for diagnosing blood disorders and overall health management.
- Diagnosis of Haemoglobin Disorders and Haemoglobinopathies: The test is crucial for identifying and diagnosing various haemoglobin disorders such as sickle cell disease, thalassaemia, and other abnormal haemoglobin variants. It allows healthcare providers to distinguish between different types of anaemias and assess the severity of the condition based on the specific haemoglobin variants detected.
- Monitoring Disease Progression: The test enables healthcare professionals to monitor the progression of haemoglobin disorders over time. By tracking changes in haemoglobin levels and the presence of abnormal variants, clinicians can assess how the disease is evolving and determine the appropriate course of treatment.
- Genetic Screening and Counselling: The hemoglobin electrophoresis test serves as a vital tool in genetic screening, helping to identify carriers of genetic conditions like sickle cell or thalassaemia. This information is invaluable for family planning decisions and genetic counselling, providing individuals and families with important insights into their genetic health
- Research and Education: Beyond clinical use, haemoglobin electrophoresis supports research efforts aimed at advancing the understanding of haemoglobinopathies. Research based on the data obtained from these tests contributes to the development of new treatments, improved diagnostic techniques, and better management strategies for haemoglobin disorders.
Who Should Get an Abnormal Hb Studies (Hb Electrophoresis) Test Done?
Certain individuals may benefit from an HPLC blood test to diagnose and monitor blood-related health conditions. Below are the categories of people who should consider routine hemoglobin electrophoresis testing:
- Individuals Exhibiting Symptoms of Blood Disorders: Symptoms like persistent fatigue, shortness of breath, and dizziness may indicate anaemia, often due to low haemoglobin levels from iron deficiency or genetic conditions. Painful swelling, growth issues, or jaundice can signal sickle cell disease, diagnosed through an HPLC blood test.
- People with Known or Suspected Blood Disorders: Individuals with a family history of haemoglobin disorders, such as sickle cell disease or thalassaemia, are at higher risk. Thalassaemia encompasses a group of inherited blood disorders that affect haemoglobin production, leading to anaemia. An Hb Electrophoresis Test is essential for diagnosing these conditions accurately and determining the specific type of haemoglobin variant present.
- Individuals with Abnormal Results from Other Blood Tests: Abnormal haemoglobin levels detected in routine blood tests may indicate the presence of a haemoglobin disorder. hemoglobin electrophoresis test provides detailed information about the types and proportions of haemoglobin variants present in the blood, aiding in the diagnosis and management of these disorders.
- Post-Blood Transfusion Patients: For individuals with sickle cell disease who have undergone blood transfusions, monitoring haemoglobin levels and identifying any changes in haemoglobin variants is crucial. Hb electrophoresis test procedure helps assess the effectiveness of transfusion therapy and ensures appropriate ongoing care.
- Pregnant Women for Screening Purposes: Pregnant women are screened for haemoglobin disorders to assess the risk of passing these conditions to their offspring. Ethnic background and family history play significant roles in determining the likelihood of being carriers or affected by haemoglobin disorders. Screening with a hemoglobin electrophoresis test allows for early detection and appropriate planning for prenatal care.
- Newborn Screening: Newborns are routinely screened for haemoglobin disorders shortly after birth. This standard practice helps identify infants with conditions like sickle cell disease or thalassaemia early on, enabling timely intervention and management to improve health outcomes.
Components of the Abnormal Hb Studies (Hb Electrophoresis) Test
Knowing the components of an HPLC blood test is crucial for accurately assessing and managing haemoglobin-related conditions. Below are the key components included in the Hb electrophoresis test list:
- Foetal Haemoglobin, Quantitative: Measures the amount of foetal haemoglobin (HbF) in the blood, which can indicate certain blood disorders like thalassaemia or hereditary persistence of foetal haemoglobin.
- Haemoglobin A (HbA): The most common type of haemoglobin in adults, accounting for about 95-98% of the haemoglobin. It consists of two alpha and two beta chains.
- Haemoglobin A2 (HbA2): A minor component of adult haemoglobin, normally making up about 2-3% of total haemoglobin. Elevated levels can indicate beta-thalassaemia.
- Haemoglobin C (HbC): A variant of normal haemoglobin A. Individuals with haemoglobin C trait have both normal and abnormal haemoglobin. Haemoglobin C disease can cause mild haemolytic anaemia.
- Haemoglobin D (HbD): A rare haemoglobin variant. Individuals with haemoglobin D trait usually have no symptoms, but haemoglobin D disease can cause mild anaemia and splenomegaly i.e. enlargement of the spleen.
- Haemoglobin S (HbS): The abnormal haemoglobin in sickle cell disease. It causes red blood cells to become rigid, sticky, and shaped like sickles, leading to various complications.
- Haemoglobin E (HbE): A common haemoglobin variant in Southeast Asia. Haemoglobin E trait is usually benign, but haemoglobin E disease can cause mild anaemia and microcytosis.
- P2 Window: A specific part of the hemoglobin electrophoresis test that helps in identifying and quantifying different types of haemoglobin present in a sample.
- P3 Window: Another part of the hemoglobin electrophoresis test. It aids in the detailed analysis and detection of minor haemoglobin variants.
- Haemoglobin: The protein in red blood cells that carries oxygen from the lungs to the rest of the body. Its levels are measured to diagnose anaemia and other blood disorders.
- RBC Count: Measures the number of red blood cells in a volume of blood. It helps diagnose conditions like anaemia, dehydration, and polycythaemia.
- PCV (Packed Cell Volume): Also known as haematocrit, it measures the proportion of blood volume occupied by red blood cells. It helps diagnose anaemia and other hematologic conditions.
- MCH (Mean Corpuscular Haemoglobin): The average amount of haemoglobin in a single red blood cell. It helps diagnose the cause of anaemia, distinguishing between microcytic and macrocytic anaemia.
- MCHC (Mean Corpuscular Haemoglobin Concentration): The average concentration of haemoglobin in a given volume of red blood cells. It is used to diagnose and classify different types of anaemia.
- MCV (Mean Corpuscular Volume): The average volume of a red blood cell. It helps determine the type of anaemia (microcytic, normocytic, or macrocytic).
- RDW (Red Cell Distribution Width): Measures the variation in red blood cell size and volume. Elevated RDW can indicate mixed anaemia or anisocytosis i.e. variation in red blood cell size.
- Peripheral Smear Finding: A microscopic examination of blood smear. It helps identify abnormalities in the size, shape, and number of blood cells, aiding in the diagnosis of various hematologic conditions.
Understanding Abnormal Hb Studies (Hb Electrophoresis) Test Report
Information about the Hb electrophoresis test normal range is crucial for preventive healthcare, aiding in the early identification of potential health risks. Below are the test ranges:
Test | Normal Range | High Range | Low Range |
Foetal Haemoglobin (HbF) | <2% in adults | >2% | Not typically a concern |
Haemoglobin A (HbA) | 95-98% of total haemoglobin | Not typically a concern | <95% |
Haemoglobin A2 (HbA2) | 2-3.5% of total haemoglobin | >3.5% | <2% |
Haemoglobin | Men: 13.8-17.2 g/dL Women: 12.1-15.1 g/dL | Men: >17.2 g/dL Women: >15.1 g/dL | Men: <13.8 g/dL Women: <12.1 g/dL |
RBC Count | Men: 4.7-6.1 million cells/µL Women: 4.2-5.4 million cells/µL | Men: >6.1 million cells/µL Women: >15.1 g/dL | Men: <4.7 million cells/µL Women: <4.2 million cells/µL |
PCV (Packed Cell Volume) | Men: 40-54% Women: 36-48% | Men: >54% Women: >48% | Men: <40% Women: <36% |
MCH (Mean Corpuscular Haemoglobin) | 27-33 picograms/cell | >33 pg/cell | <27 pg/cell |
MCHC (Mean Corpuscular Haemoglobin Concentration) | 32-36 g/dL | >36 g/dL | <32 g/dL |
MCV (Mean Corpuscular Volume) | 80-100 femtolitres | >100 fL | <80 fL |
RDW (Red Cell Distribution Width) | 11.5-14.5% | >14.5% | Not typically a concern |
Test | Normal Findings | Abnormal Findings |
Haemoglobin C (HbC) | Not present | Present |
Haemoglobin D (HbD) | Not present | Present |
Haemoglobin S (HbS) | Not present | Present |
Haemoglobin E (HbE) | Not present | Present |
P2 Window | Not applicable | Deviations indicate the presence of abnormal haemoglobins |
P3 Window | Not applicable | Deviations indicate the presence of abnormal haemoglobins |
Peripheral Smear Finding | Normal size, shape, and appearance of red blood cells (RBCs), white blood cells (WBCs), and platelets. | Changes in RBC size, shape, or colour. Abnormal WBC types or numbers. Abnormal platelet numbers. Presence of immature or abnormal cell types |
The condition or disease indicated by abnormal levels are given below:
Test | High Value Indicates | Low Value Indicates |
Foetal Haemoglobin (HbF) | Thalassaemia which is an inherited blood disorder affecting haemoglobin production. Sickle Cell Disease, a genetic condition causing abnormal haemoglobin, leading to sickle-shaped red blood cells. Hereditary Persistence of HbF: Genetic condition where foetal haemoglobin persists into adulthood. | Not typically a concern |
Haemoglobin A (HbA) | Not typically a concern | Haemoglobinopathies, i.e. genetic disorders affecting haemoglobin synthesis. Beta-Thalassaemia: Inherited blood disorder resulting in reduced production of beta-globin chains. |
Haemoglobin A2 (HbA2) | Beta-Thalassaemia Trait | Iron Deficiency Anaemia: Lack of iron leading to reduced haemoglobin production. Alpha-Thalassaemia which is a deficiency in alpha globin chains of haemoglobin. |
Haemoglobin | Polycythaemia i.e. increased red blood cell count | Anaemia i.e. decreased red blood cell count or haemoglobin levels. |
RBC Count | Polycythaemia | Anaemia |
PCV (Packed Cell Volume) | Polycythaemia | Anaemia |
MCH (Mean Corpuscular Haemoglobin) | Macrocytic anaemia wherein red blood cells are larger than normal. | Microcytic anaemia wherein red blood cells are smaller than normal. |
MCHC (Mean Corpuscular Haemoglobin Concentration) | Spherocytosis: Genetic disorder causing spherical-shaped red blood cells. | Hypochromic Anaemia i.e. red blood cells with low haemoglobin content. Iron Deficiency Anaemia |
RDW (Red Cell Distribution Width) | Mixed anaemia Anisocytosis i.e. variation in red blood cell size. | Not typically a concern |
Test | Presence Indicates |
Haemoglobin C (HbC) | Sickle Cell Disease with HbC, the individuals have both sickle cell trait (HbS) and haemoglobin C trait (HbC), resulting in varying symptoms of anaemia and potential complications. Haemoglobin C Disease, an inherited blood disorder where the beta-globin protein is abnormal due to a mutation leading to mild chronic haemolytic anaemia. |
Haemoglobin D (HbD) | Haemoglobin D Disorders: It is a genetic condition where haemoglobin D variants (HbD) are present, causing varying degrees of haemolytic anaemia depending on the specific mutation. Sickle Cell Disease with HbD: Coexistence of sickle cell trait (HbS) and haemoglobin D trait (HbD), leading to symptoms of sickle cell disease with additional characteristics of haemoglobin D disorders. |
Haemoglobin S (HbS) | Sickle Cell Disease, Sickle Cell Trait |
Haemoglobin E (HbE) | Haemoglobin E disorders, a condition involving haemoglobin E variant (HbE), which can lead to mild to moderate anaemia and may combine with beta-thalassaemia to cause more severe symptoms. Beta-Thalassaemia with HbE: Combination of beta-thalassaemia (reduced or absent beta-globin production) with haemoglobin E variant, causing anaemia and other related symptoms. |
P2 Window | Various abnormal haemoglobinopathies which is a broad category encompassing genetic disorders affecting haemoglobin structure or production, leading to abnormal haemoglobin patterns on electrophoresis |
P3 Window | Various abnormal haemoglobinopathies |
Peripheral Smear Finding | Abnormal peripheral smear findings, such as microcytic and hypochromic red blood cells, suggest conditions like iron deficiency anaemia and thalassemia. The Presence of sickle-shaped RBCs indicates sickle cell disease, while immature RBCs (reticulocytes) and abnormal white blood cells (blasts) point to haemolytic processes, leukaemia, or infections like malaria. Thrombocytopenia denotes decreased platelet counts. |
Preparation and Procedure for Abnormal Hb Studies (Hb Electrophoresis) Blood Test
Proper Hb electrophoresis test preparation is crucial to ensure precise and accurate test outcomes essential for subsequent diagnosis.
How is the Abnormal Hb Studies (Hb Electrophoresis) Test Done?
The hemoglobin electrophoresis test is a straightforward and fast procedure where a blood sample is taken from a vein in your arm.
- A doctor or trained healthcare professional will draw a small amount of blood from a vein in your arm using a fine needle. This blood sample is then collected in a vial or test tube for analysis. The collected blood sample will be sent to a laboratory where the different types of haemoglobin in the serum will be evaluated.
- While you might feel a slight sting as the needle pierces your skin for the blood sample, the process is usually quick, typically lasting less than five minutes.
- Occasionally, you may experience some pain or bruising at the site where the needle was inserted, but these symptoms resolve quickly.
Is Fasting Required for the Abnormal Hb Studies (Hb Electrophoresis) Test?
Fasting is typically not required for an HPLC blood test.
- Your healthcare provider may recommend temporary cessation or adjustment of certain medications to avoid interference with the test.
It's always best to follow the advice of your family physician for the Hb electrophoresis test preparation to ensure accurate results.
What Time of the Day Should I Undergo an Abnormal Hb Studies (Hb Electrophoresis) Test?
One crucial aspect to consider when undergoing the Hb electrophoresis test is timing. Individuals can undergo the test at any time of the day.
- Most doctors recommend taking this test early in the morning at an ESR lab. Early appointments help ensure accurate results and timely diagnosis.
However, always consult your doctor about timings as they may vary based on personal health conditions and other factors.
Booking Abnormal Hb Studies (Hb Electrophoresis) Test Online & Checking Reports
Online healthcare services offer significant convenience, particularly beneficial for elderly individuals, pregnant women, and those with restricted mobility. This section provides a step-by-step outline for booking the Hb electrophoresis test online through Apollo 24|7 and accessing the test report once it becomes available.
What are the Steps to Schedule the Abnormal Hb Studies (Hb Electrophoresis) Test on Apollo 24|7?
Booking a hemoglobin electrophoresis test via Apollo 24|7 is simple and convenient. The process is user-friendly and can be completed swiftly from the comfort of your own home. Below are the steps involved:
- Visit Apollo 24|7 Website or App: To initiate the process, access the official Apollo 24|7 website or install their app on your mobile device. The design is intuitive and optimised for easy navigation.
- Search for the Test: On reaching the homepage, locate the search box, typically at the top of the page. Type in "hemoglobin electrophoresis test". This will take you directly to the page dedicated to this crucial blood test.
- Choose a Convenient Time and Location: Now that you're on the hemoglobin electrophoresis test page, you can select a time slot and location that fits your schedule for your blood sample collection. You can also look up Hb electrophoresis test procedure near your location to find the relevant details.
- Complete Your Booking: Once you've chosen your preferred time and location, proceed to complete your booking by entering all required details.
- Wait for Confirmation: After you've placed an order for your Hb electrophoresis test procedure, simply wait for a confirmation message from Apollo 24|7. This last step ensures that your request has been accurately processed.
How do I Access my Abnormal Hb Studies (Hb Electrophoresis) Test Results Online on Apollo 24|7?
Once your blood sample has been collected, follow these simple steps to access, review, and download your Hb electrophoresis test report through the Apollo 24|7 platform:
- Await Notification: Apollo 24|7 will send you a notification when your test results are ready for viewing.
- Log into Your Account: Access your account on the Apollo 24|7 website or mobile app using your registered login credentials.
- Go to the Reports Section: Upon successful login, navigate to the designated 'Reports' section where all your medical test results are stored.
- Find 'Erythrocyte Sedimentation Rate Test': Locate the specific entry for your hemoglobin electrophoresis test within the available reports.
- Download Your Report: Look for the option to download and save your test report. This feature enables you to keep a copy of your Hb electrophoresis test report for future reference or to share with your doctor.
Frequently Asked Questions (FAQs)
If my hemoglobin electrophoresis test blood test results are positive, what are the next steps? Should I consult a specialist or make specific lifestyle changes?
Are there any alternative or complementary tests to consider alongside an HPLC blood test for a more comprehensive assessment?
Are there any emerging technologies or advancements in hemoglobin electrophoresis test testing that I should be aware of?
Can I drink water before an HPLC blood test?
How accurate is the hemoglobin electrophoresis test for the diagnosis of blood-related disorders?
How long does it take to get the results of an HPLC blood test?
Can abnormal haemoglobin levels be fatal?
What can affect the results of my hemoglobin electrophoresis test?
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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results