My dad's 76 and a few years back he was diagnosed with triple vessel coronary artery disease and lmca disease. Three years ago, he had an angioplasty and got a stent put in for one of his major artery blocks. The cardiologist suggested we manage the two other 100% blocks with medical management instead of more procedures because of some complications. Small hitch though, post-angioplasty, his kidneys were affected and his creatine level hit 1.6. He's been maintaining it between 1.6 to 1.8 with a strict diet for almost three years now. Recently, his cardiologist changed up his meds to boost his heart function and put him on Isolazine. Now, his blood pressures gone up and one of his legs is swelling. I'm stuck wondering if its fluid retention but is it from his heart or his kidneys acting up? Should we be worried about Isolazine for his kidney health? Hes been on it for around four months. Could it be related? What's your take on this?

Isolazine is not recommended for patients with kidney issues, as it can potentially worsen kidney function and cause fluid retention, which may present as leg swelling. It is advisable to stop Isolazine and consult with the cardiologist for an alternative medication that is safer for kidney function. In the meantime, it is important to monitor his blood pressure closely and manage any fluid retention symptoms.