I've been feeling a strange vibration in my chest after running and sometimes while I'm running. Its kind of weird and Im a bit worried. Two years back, my TMT, echo, and ECG came out normal, and I even had a CT angiogram a year ago, which was fine. My Holter monitor results were okay too. What could be causing this sensation, and should I be concerned about something else going on?

It sounds like you may be experiencing palpitations or a sensation of vibration in your chest during or after running. Since your TMT, echo, ECG, CT angiogram, and Holter monitor have been normal in the past, it is less likely to be related to any structural or electrical heart issues. One possible cause could be related to increased sympathetic activity during exercise. It is important to stay hydrated and ensure you are not overexerting yourself during physical activity. If the symptoms persist or worsen, you may consider discussing with your doctor about trying a beta-blocker medication such as Metoprolol (dosage can vary) to help control heart rate and palpitations during exercise.