apollo
  • Male
  • 31 Years
  • 22/01/2025

Hey, I've got a question about the P24 antigen antibody test. If I take it a month after possible exposure, will the results be conclusive for HIV, or should I consider getting another type of test too? I'm anxious to know how accurate it really is at that point.

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Answered by 1 Apollo Doctors

The P24 antigen-antibody duo test is highly accurate when done after one month of potential exposure, as it detects both the HIV virus and antibodies. However, for a conclusive result, it's recommended to confirm with a follow-up test, such as the HIV RNA PCR test or another antibody test, at 3 months post-exposure.

Dr. Shubham Suggests...

Consult a Infectious Disease specialist

Answered 04/07/2025

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  1. Understanding the P24 Antigen Antibody Test

    • The P24 antigen antibody test detects HIV antigens and antibodies, indicating early infection.
    • It differs from other tests by identifying the virus sooner than antibody-only tests.
  2. Timing and Accuracy of the Test at One Month Post-Exposure

    • The P24 test is typically accurate from 2-4 weeks post-exposure.
    • At one month, it is generally reliable, but not definitive for all cases.
  3. Recommendations for Additional Testing

    • Follow-up testing is advised to confirm results.
    • Consider a nucleic acid test (NAT) or a fourth-generation test for comprehensive results.
  4. Consulting Healthcare Professionals

    • Discuss results and timing with a healthcare provider for personalized advice.
    • They can guide you on next steps based on your risk factors and test outcomes.
  5. Emotional Support and Confidentiality

    • Seek support and maintain confidentiality during testing and follow-up.
    • Professional guidance can provide reassurance and clarity.

Recommended next steps

Consult a Infectious Disease specialist or Consult a Sexologist

Answered 20/08/2025

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I had unprotected sex about a year ago and then tested positive for HSV 12 IgG. Now, after a year, I got retested and it shows negative for HSV. But, whats worrying me is that my Western Blot test says HIV 1 is indeterminate with HIV 1 p24 GAG detected, and HIV 2 is not detected. Also, the HIV 12 ELISA test is negative and the HIV 1 RNA quantitative PCR test shows 'Target Not Detected'. I'm really anxious about what this means. Do I have HIV? What should be my next steps? I'm really hoping for some guidance on how to interpret these results.

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Disclaimer: Answers on Apollo 247 are not intended to replace your doctor advice. Always seek help of a professional doctor in case of an medical emergency or ailment.