Urine- Bence Jones Proteins

Bence Jones Syndrome, also known as Light Chain Deposition Disease (LCDD), is a rare medical condition related to abnormal proteins in the body. It is formed by the deposition of monoclonal immunoglobulin light chains (Bence Jones proteins) in various organs and tissues throughout the body. It is typically a result of abnormal plasma cells in the bone marrow. While it is believed that genetic factors, age, chemical exposure, and immune system issues are potential contributors, the exact cause remains unclear. Their presence in the urine is a diagnostic hallmark of multiple myeloma, a type of blood cancer.

Some of the symptoms of Bence Jones Syndrome are:

• Signs of organ damage due to the deposition of abnormal antibodies in the body
• Kidney dysfunction and proteinuria
• Heart problems, including cardiomyopathy
• Nerve damage and symptoms like numbness, tingling, and weakness
• Digestive issues
• Sudden changes and abnormalities in the skin

Urine-Bence Jones Protein Test is recommended by a doctor when:

• a patient experiences symptoms such as constant feelings of tiredness or kidney problems without a clear cause
• routine blood tests show unusual findings, such as high protein levels, abnormal kidney function, or low blood count
• individuals already diagnosed with multiple myeloma or related disorders require monitoring of the progression of the disease to evaluate the effectiveness of ongoing treatment
  there's uncertainty about conditions related to abnormal plasma cell protein production

The process of a Urine-Bence Jones Proteins test begins with the clinical evaluation of the patient's symptoms and medical history. It is conducted by the clean-catch method or the 24-hour method. This requires the person to collect all the urine they pass in 24 hours, as the components of urine change over the day. When the sample reaches the lab, the urine is analysed, primarily using immuno-electrophoresis or immuno-fixation, to detect the presence of monoclonal immunoglobulin light chains or the Bence Jones proteins. Once the results are reported, further clinical and laboratory assessment is done to diagnose the underlying conditions which is then utilised in planning the treatment for each individual.

If the reports from a Urine-Bence Jones Proteins test are positive, it is typically suggestive of an underlying condition, most commonly multiple myeloma which is a type of blood cancer or a related plasma cell disorder. The immediate steps to take after a positive report of this test are:

• Seek immediate consultation with a haematologist or oncologist.
• Get further evaluation as additional tests may be necessary to confirm the diagnosis, determine the disease stage, and assess its impact on various organs.
• Discuss treatment options with your healthcare team about available treatment options.
• Work with your healthcare team to create a personalised treatment plan tailored to your specific condition, needs, and preferences.

Apollo 24|7 provides the most reliable healthcare at your convenience. Some key benefits of the Urine-Bence Jones Proteins test at Apollo 24|7 are:

• Accurate diagnosis
• Early detection
• Personalised treatment
• Reduced risk of complications
• Urine-Bence Jones Proteins Test price at Apollo 24|7 is competitive

So don't wait any longer! Take your first step towards healthcare.