Anti Gliadin - IgA

Celiac disease is a condition that is characterised by adverse immunological response to intake of gluten, a type of protein found in wheat, barley, and rye. People with celiac disease have immune systems that identify gluten as a harmful foreign substance. As a result, such systems produce antigliadin antibodies to attack this protein.

Here are the common effects of celiac disease:

• Abdominal pain
• Gas
• Diarrhoea
• Heartburn
• Weight loss
• Headache
• Constipation

In some cases, this illness can also lead to a loss of bone density. During this allergic reaction, your body releases Immunoglobin A (IgA) and Immunoglobulin G (IgG) antibodies. Hence, detection of IgG and IgA gliadin antibodies is crucial to determine the presence of celiac disease.

However, testing for IgA antibodies proves more helpful due to the location of this antibody. Immunoglobin A is present in the small intestine. Gluten produces inflammation in this part of the body. Hence, analysing anti-gliadin IgA levels can establish the severity of the illness.

This condition can arise if you have the following risk factors:

• Lupus
• Type 1 diabetes
• Down syndrome
• Psoriasis
• Intestinal lymphoma
• Addison’s disease
• Autoimmune hepatitis
• Rheumatoid arthritis

Hence, undergoing an anti-gliadin IgA test is crucial to avoid certain celiac disease complications. In some cases, you can suffer from malnutrition, weak bones, and lactose intolerance due to this disorder. For this purpose, it is essential to compare your results with the anti-gliadin IgA normal range.

Your doctor can recommend testing for IgA antibodies to discover the possibility of celiac disease. This IgA gliadin test is a simple blood evaluation. A health professional will draw a small amount of blood from your arm to gather the specimen.

The lab technician will use a sterilised needle for venipuncture during this process. Hence, the gliadin antibodies test will not pose considerable risks. You might feel mild bruising and pain during blood sample extraction. A positive Immunoglobulin A report indicates the presence of infection.

The quantity of antigliadin antibodies serves as a base for understanding the severity of infection. Before undergoing the anti-gliadin IgA test, you should consult your physician about ongoing medications. Generally, deficiency in IgA levels can lead to false-negative test results. Hence, ensure that you are well-equipped by following the recommendations of medical experts.

To get timely results, choosing an experienced antigliadin antibodies test provider is vital.

Apollo 24|7 offers this testing at competitive rates. You can receive the reports within a span of nine days in most cases. After acquiring the anti-gliadin IgA levels report, remember to share the report with your physician. Analysis of these results will initiate a gluten-free diet that can control celiac disease symptoms.  
 

Medically reviewed by Dr. P Siva Charan Reddy, Surgical gastroenterologist, Apollo Hospitals Jubilee Hills, Hyderabad.