Anti Cardiolipin Antibody Panel (IgA+IgG+IgM) (Elisa Method)

The Anti-Cardiolipin Antibody Panel test is a diagnostic evaluation that investigates abnormal blood clot formation and determines the cause of recurrent miscarriage. It may even be asked to diagnose antiphospholipid syndrome (APS) or similar autoimmune diseases. These antibodies are produced by the immune system and mistakenly target the body’s cardiolipins.

Cardiolipins are substances found in the outermost layer of cells and platelets. As a result, they can affect the body’s blood clot regulation ability in an unnatural way. This anti-cardiolipin antibody panel test helps in detecting the presence of cardiolipin antibodies in the blood. If you have suffered from one or more abnormal blood clots in an artery or a vein, have symptoms consistent with an autoimmune disease, or have had recurrent miscarriages, then it’s advisable to get yourself tested with an anti-cardiolipin antibody test.

The anti-cardiolipin antibody panel test includes IgA+IgG+IgM tests. Getting this test done is critical to assess the causes of abnormal blood clotting and miscarriages. Anti-cardiolipin antibodies generally target a person’s cardiolipins and put the patient at a high risk of developing recurrent blood clots in deep veins of the legs, arteries, or the lungs.

This anti-cardiolipin antibody panel test is evaluated using the ELISA (Enzyme Linked Immunosorbent Assay) method to get the results. Testing is usually prescribed by doctors or healthcare providers in cases of excessive, recurring, and abnormal blood clotting. The signs and symptoms usually vary, depending on the clot location.

A negative anti-cardiolipin antibody test result indicates that cardiolipin antibodies are not present or not available in detectable levels in the blood during the test. These antibodies are the most common of the antiphospholipid antibodies. Low to moderate levels are not significant but must be monitored with signs and symptoms. Moderate to high levels are associated with an increased risk of excessive clotting.

If the cardiolipin antibodies are detected after an initial anti-cardiolipin antibody test, the test is usually repeated after 12 weeks to evaluate whether their presence is constant or temporary. Suppose a person with an autoimmune disorder has a negative test result for cardiolipin antibodies. In that case, they may be retested later as the antibodies can force themselves to develop anytime in the future.

There are mainly three classes of cardiolipin antibodies present in the blood- IgG, IgM, and/or IgA. The most common ones that are tested are IgG and IgM. However, if the results are negative and the healthcare providers may suspect the clinical presence of these antibodies, then an IgA cardiolipin antibody test may be ordered again.

At Apollo 24|7, you can book the anti-cardiolipin antibody panel test and begin the appropriate treatment by consulting your healthcare provider.

Here are some of the reasons why your doctor might ask you to get the anti-cardiolipin antibody panel test done:

• Excessive blood clots in deep veins of the legs
• If the blood clots affect the lungs and cause shortness of breath or rapid heart rate
• If a woman has had recurrent miscarriages