Anti Sperm Anti Bodies

Antisperm antibodies are immune system proteins that fight sperm. They are also responsible for destroying it as they are produced sperm is considered as an invader and triggers a defence response. Antisperm antibodies are generally found in blood, semen, or vaginal fluids.

When an individual is tested positive for antisperm antibodies, their presence can negatively impact their fertility. An individual may experience motility, sperm count reduction, and effects on sperm-egg interaction.

In men, antisperm antibodies are produced after there is an injury to the testicles or after surgery has been performed on them. These antibodies can also be produced when the barrier between separating the sperm from the immune system (blood-testis barrier) is broken. Due to this, the sperm reaches the immune system, and antisperm antibodies form.

The leading cause of antisperm antibodies is vasectomies. According to medical studies and research, around 50% of men with vasectomies develop antisperm antibodies. While in other cases of vasovasostomies, the occurrence of antisperm antibodies is not always reduced. Additionally, other surgeries such as testicular biopsies can also lead to antisperm antibodies.

Trauma caused by testicular torsion or prostate infection can also cause the production of antisperm antibodies in men. Prostate infection leads to anti- as well as pro-oxidative factor imbalance in male semen. Because of this, antisperm antibodies are formed.

In women, antisperm antibodies are found in the reproductive system. They are usually produced when the female body reacts to sperm as though it were an invader. This leads to an allergic reaction-like response. Some conditions may increase the risks and possibilities of developing antisperm antibodies in women.

The formation of these antisperm antibodies can contribute to infertility in both men and women. 
Anti-sperm antibodies test is a valuable step in providing substantial information about fertility. At Apollo 24|7, you can opt for an antisperm antibodies test if you face any of the following symptoms:

• If you experience unexplained infertility
• In cases of sperm agglutination or sticking together of sperms 
• People with in vitro fertilisation

If you are having a challenging time getting pregnant with your partner, you may appear for an anti-sperm antibodies test to check for their presence. Treatment may differ for men and women. For men, healthcare providers or doctors may prescribe medication to lower the body's immune response.

For women, intrauterine insemination is one treatment method that has shown promising results.