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anti lkm-1 antibody

Anti LKM-1 Antibody

Q: What does a positive smooth muscle antibody indicate?

The amount of positive smooth muscle antibody (SMA) determines the presence of autoimmune hepatitis infection. Your doctor can recommend this testing to detect such antibodies along with the anti-LKM-1 test. Higher amounts of these antibodies imply a type I autoimmune hepatitis infection. On the other hand, a lower amount of SMAs may indicate type II autoimmune hepatitis infection.

Q: How severe is autoimmune hepatitis?

Untreated autoimmune hepatitis can scar the liver tissues. This condition is known as cirrhosis, which leads to liver failure. However, you can suppress the immune system and treat this disease with a timely diagnosis. For this purpose, it is vital to undergo the LKM antibody test.

Q: What is the difference between type I and II autoimmune hepatitis?

Type I autoimmune hepatitis is comparatively less severe and occurs in adulthood. On the contrary, type II autoimmune hepatitis appears during childhood and can be difficult to control. In both scenarios, your body produces the liver-kidney microsomal antibody. Hence, quick testing and treatment become vital.

Q: Which other tests can prove helpful in confirming autoimmune hepatitis?

In addition to the LKM antibody test, you can confirm autoimmune hepatitis using other liver evaluations. Some of these blood tests are aspartate transaminase, alanine transaminase, anti-smooth muscle antibody, and antinuclear antibody.

Q: Which health condition affects smooth muscle?

The condition known as Multisystemic Smooth Muscle Dysfunction Syndrome affects smooth muscles in the body. It is a rare genetic condition that can lead to hypotonic bladder, cerebrovascular disease, and other malfunctions.

Q: What does the presence of autoantibodies in the liver indicate?

Autoantibodies are serological hallmarks of an autoimmune disease. They attack your body’s self-cellular nucleic acids and proteins. For instance, the LKM-1 antibodies are a prime example of such bodily malfunctioning. These autoantibodies are clear signs of autoimmune disorders in your liver.

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ANTI LKM-1 ANTIBODY
1 test included

About

SAMPLE TYPE

BLOOD

GENDER

Both

AGE GROUP

7 years & above

Acute liver failure is a health condition in which your liver cells become dysfunctional. This state results from diseases like hepatitis and can often result from various viruses and toxins. During this condition, your body produces the liver-kidney microsomal antibody (LKM). The presence of an LKM antibody is a sign that your system is targeting the antigens that contribute to chronic liver failure.

Depending on the disease, your body produces three different types of antibodies:

LKM-1 antibodies: Marker for autoimmune hepatitis II and hepatitis C
LKM-2 antibodies: Marker for tienilic acid-induced hepatitis
LKM-3 antibodies: Marker for hepatitis D and autoimmune polyendocrine syndrome type 1

Hence, your doctor can recommend an anti-LKM-1 test to diagnose the presence of liver-kidney microsomal antibody type 1. Such medical evaluation helps establish whether you have autoimmune hepatitis or facing potential liver damage.

You might need to undergo the anti-LKM-1 test if you face the following symptoms:

Jaundice
Skin rashes
Joint pain
Abdominal discomfort
Enlarged liver
Dark urine
Vomiting
Mental confusion

The doctor can assess these symptoms and recommend a proper medical evaluation. In such cases, your body can produce an LKM antibody similar to the IgG antibodies mechanism. Hence, the result of this testing helps identify the leading cause of the symptoms.

An anti-LKM-1 test is a simple blood test that does not require any special preparations. This medical test includes a venipuncture process, in which the lab technician inserts a needle into your vein. After the extraction, the lab professionals study your specimen and compare it with the LKM antibody normal range.

A positive result indicates the presence of antibodies in your blood. A high amount of LKM-1 antibodies indicates the possibility of type II autoimmune hepatitis.
Your doctor may suggest a smooth muscle antibody (SMA) test to diagnose type I autoimmune hepatitis.

Also, you may need to undergo an antinuclear antibody (ANA) test to confirm if your body is attacking its own tissues. The need for these additional tests depends on your medical professional’s advice. A history of chronic hepatitis C can be one of the leading factors for positive LKM antibody results.

During the blood test, you may feel itching or pain at the site of the needle. However, availing this test from a reliable medical lab can reduce the chances of such risks. Apollo 24|7 offers a comprehensive anti-LKM-1 test at competitive rates.

Frequently Asked Questions (FAQs)

What does a positive smooth muscle antibody indicate?
The amount of positive smooth muscle antibody (SMA) determines the presence of autoimmune hepatitis infection. Your doctor can recommend this testing to detect such antibodies along with the anti-LKM-1 test.

Higher amounts of these antibodies imply a type I autoimmune hepatitis infection. On the other hand, a lower amount of SMAs may indicate type II autoimmune hepatitis infection.
How severe is autoimmune hepatitis?
Untreated autoimmune hepatitis can scar the liver tissues. This condition is known as cirrhosis, which leads to liver failure. However, you can suppress the immune system and treat this disease with a timely diagnosis. For this purpose, it is vital to undergo the LKM antibody test.
What is the difference between type I and II autoimmune hepatitis?
Type I autoimmune hepatitis is comparatively less severe and occurs in adulthood. On the contrary, type II autoimmune hepatitis appears during childhood and can be difficult to control. In both scenarios, your body produces the liver-kidney microsomal antibody. Hence, quick testing and treatment become vital.
Which other tests can prove helpful in confirming autoimmune hepatitis?
In addition to the LKM antibody test, you can confirm autoimmune hepatitis using other liver evaluations. Some of these blood tests are aspartate transaminase, alanine transaminase, anti-smooth muscle antibody, and antinuclear antibody.
Which health condition affects smooth muscle?
The condition known as Multisystemic Smooth Muscle Dysfunction Syndrome affects smooth muscles in the body. It is a rare genetic condition that can lead to hypotonic bladder, cerebrovascular disease, and other malfunctions.
What does the presence of autoantibodies in the liver indicate?
Autoantibodies are serological hallmarks of an autoimmune disease. They attack your body’s self-cellular nucleic acids and proteins. For instance, the LKM-1 antibodies are a prime example of such bodily malfunctioning. These autoantibodies are clear signs of autoimmune disorders in your liver.

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The information mentioned above is meant for educational purposes only and should not be taken as a substitute to your Physician’s advice. It is highly recommended that the customer consults with a qualified healthcare professional to interpret test results