I recently had a urine culture done at a local lab, and it showed 80,000 E. coli count. Ive had this issue before, and a few months ago, the same lab gave the same result. I was prescribed antibiotics for two weeks, and after a short break, I did another urine culture test, but it still showed E. coli. The urologist changed my medication, but now its back again.I also had an ultrasound KUB, and it came out normal. I did a semen culture, which showed another infection, and after more antibiotics, it still showed an infection. The urologist here is unable to figure out whats going on.Ive been having sharp pains in my abdomen and rectum sometimes, and my urine has a bad smell. Im really worried about this recurring infection. Can you suggest any further tests or possible reasons why the E. coli keeps coming back, and why the semen culture keeps showing infections? What should I do next?

It sounds like you're dealing with a persistent E. coli infection that may not have fully cleared despite antibiotics. Chronic or recurrent infections can be due to incomplete treatment, an underlying issue like a urinary tract abnormality, or antibiotic resistance. It's important to consider a urine culture with antibiotic sensitivity testing, possibly imaging studies beyond ultrasound (like CT or MRI), and reviewing the semen culture results to address any underlying causes. A urologist or infectious disease specialist could help explore further options.