I have Acanthosis Nigricans and the skin around my knees is getting darker and thicker. Are there any good home remedies to lighten the skin or reduce the thickening? I'm looking for something that might help with this condition.

For Acanthosis nigricans, it is important to address the underlying cause, such as obesity or insulin resistance. In addition to medical treatment, you can try using over-the-counter creams containing ingredients like retinoids or alpha hydroxy acids to help lighten the darkened skin. Moisturizing regularly can also help improve the appearance of the affected areas. To address the thickened skin in Acanthosis nigricans on the knees, you can try using a keratolytic cream containing ingredients like salicylic acid or urea to help soften and exfoliate the skin. Regular exfoliation and moisturizing can also help improve the texture of the skin on the knees.